Job Description

WHO WE ARE

ODDITY is a consumer tech platform transforming the global beauty and wellness market. We deploy advanced technology, including molecular discovery, synthetic biology, artificial intelligence, machine learning, and computer vision to develop exceptional products and deliver consumers a superior experience. Our digital-first brands, IL MAKIAGE and SpoiledChild, are rapidly disrupting the offline-dominated beauty and wellness industries around the world. Brands 3 and 4 will launch next year, replicating the playbook of our existing brands in adjacent spaces to take a step change in our growth and impact.

ODDITY Labs is our cutting-edge biotechnology R&D center, powering product innovation through the discovery of new molecules that will power game changing products through ODDITY's current and future brands. Our exceptional team is passionate about using biology, chemistry, and technology to disrupt consumers' product expectations and shopping journeys, shifting millions of consumers from offline to online along the way. Our culture is fast-paced, innovative, agile, and offers every team member the opportunity to drive a big impact.

We are looking for the ideal Medicinal

We are seeking an experienced and strategic Principal Scientist to lead our efforts in translational skin biology, driving the development and validation of novel approaches across our discovery and development pipeline. You will work cross-functionally with chemistry, pharmacology, and formulation teams to advance programs from target validation through preclinical studies. You are a strategic thinker who excels in designing and executing translational biology studies, applying in vitro and ex vivo, and integrating complex data into actionable insights. This individual thrives in fast-paced, results-driven environments, is highly collaborative across disciplines, and brings a proactive approach to managing multiple projects under tight timelines.

WHAT YOU WILL DO

• Lead and execute translational biology studies with a focus on skin biology, using in vitro and in vivo models to evaluate efficacy, mechanism of action, and safety.
• Design, implement, and optimize assays for skin-relevant endpoints, including collagen, elastin, hyaluronic acid, pigmentation, inflammation, and barrier function.
• Develop and validate biomarkers of skin health and aging to support target validation and preclinical proof-of-concept.
• Collaborate with cross-functional partners (chemistry, pharmacology, formulation, and clinical) to align biological strategy with program goals.
• Manage and guide external CRO relationships for biological assays, skin models, and advanced analytical testing.
• Contribute to program strategy by interpreting biological data and translating findings into actionable insights for compound advancement.
• Ensure rigorous experimental design, data analysis, and clear communication of results to internal stakeholders and external collaborators.
• Maintain awareness of emerging technologies in skin biology and dermatological research, driving innovation in models and methodologies.
• Advance projects from target validation through preclinical development, ensuring delivery of high-quality data packages that support decision-making and regulatory readiness.

WHO YOU ARE

• Ph.D. (or equivalent experience) in Biology, Dermatology, Pharmacology, or a related life science field with a strong focus on skin biology and translational research .
• 7+ years of industry experience in translational biology, preclinical research, or related areas, ideally within dermatology, cosmetics, or skin-focused therapeutics.
• Proven expertise in designing and executing in vitro and in vivo skin models to assess efficacy, safety, and mechanism of action.
• Hands-on experience with skin-relevant endpoints such as collagen, elastin, hyaluronic acid, pigmentation, inflammation, and barrier integrity.
• Strong knowledge of biomarkers for skin health, aging, and disease, with the ability to integrate biological data into development strategies.

WHAT WE OFFER

• Competitive compensation and benefits package.
• This position will consider and sponsor candidates on a visa (OPT, STEM OPT, H1B, TN).
• This position is in-office in our Cambridge, Massachusetts office and laboratory.
• The salary for this position is negotiable and commensurate with experience.

Note : We’re currently hiring for many roles! Not the right fit, but interested in another position? Contact us olabs.jobs@oddity.com

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